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The limitations of the study include its small sample size, which precluded the selection of a control group of patients without diabetes and with periodontal disease

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scFv TS2/16 production in Expi293 cells The coding sequence of the TS2/16 scFv (V H V L orientation) containing the artificial human kappa L-chain signal sequence, and C-terminal tags (8His tag), HRV 3C site (LEVLFQ/GP), Fc-tag (huIgG1) and a stop codon, was cloned into the pcDNA3.1 mammalian expression vector (Extended Data Fig

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CMS established two conversion factors for the first time: $33.40 per RVU for non-APM participants and $33.57 for APM participants